비아그라에 대한 주요 지침
비아그라에 대한 주요 지침
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VIAGRA has sildenafil, which is identical drugs found in another drug referred to as REVATIO. REVATIO is made use of to take care of a scarce illness named pulmonary arterial hypertension (PAH).
Sildenafil improves the outcome of NO by inhibiting phosphodiesterase sort five (PDE5), that is chargeable for degradation of cGMP inside the corpus cavernosum. Sildenafil has no immediate relaxant impact on isolated human corpus cavernosum.
As a consequence of superior plasma protein binding and lousy elimination in urine, elimination through hemodialysis is unlikely.
Although there have been no severe adverse occasions probably linked to blood pressure reported Within this study, a person subject matter documented moderate vasodilatation after both of those VIAGRA 50 mg and a hundred mg. There were no episodes of syncope reported With this research.
Outcomes of Other Drugs on VIAGRA Sildenafil metabolism is principally mediated by CYP3A4 (main route) and CYP2C9 (minimal route). Therefore, inhibitors of these isoenzymes may possibly cut down sildenafil clearance and inducers of such isoenzymes might boost sildenafil clearance.
VIAGRA shouldn't be utilised with REVATIO or with other PAH treatments containing sildenafil or every other PDE5 inhibitors (for example Adcirca [tadalafil])
sudden eyesight loss in a single or the two eyes. Unexpected vision decline in one or both of those eyes generally is a sign of a significant eye issue identified as non-arteritic anterior ischemic optic neuropathy (NAION). Quit getting VIAGRA and 비아그라 구매 contact your healthcare service provider immediately if you have any unexpected eyesight reduction
Your personal medical professional will require to be aware of regarding your health and fitness, where by your non-public responses regarding your prescription drugs, Life style selections, prior surgeries, and ED can help your physician comprehend the proper treatment for yourself. They’ll also require a current hypertension (within just previous 6 months) looking at, Together with a personal ID so that they know who They are going to be Individually aiding.
In adults sixty five years or more mature, use warning with dose collection as a consequence of a higher incidence of compromised renal, cardiac, and/or hepatic function, and of concomitant sickness or drug therapy.
Using VIAGRA provides no safety versus sexually transmitted illnesses. Counseling 비아그라 구입 of individuals with regards to the protecting actions needed to guard from sexually transmitted disorders, such as the Human Immunodeficiency Virus (HIV), could possibly be regarded.
It is actually 정품비아그라구매 eliminated predominantly by hepatic metabolism (mostly CYP3A4) and is particularly converted to an Energetic metabolite with properties comparable to the 정품비아그라 guardian, sildenafil. Both of those sildenafil and also the metabolite have terminal 50 % lives of about 4 hours.
These 정품비아그라 kinds of combinations might further lessen hypertension. For that reason, the use of these types of mixtures isn't recommended.
Discuss with a licensed physician in your condition free of charge. If prescribed, get your ED medication delivered in lower than forty eight hours, shipped discretely for you.
For anyone who is getting sildenafil to deal with erectile dysfunction, explain to your health practitioner Should you have ever been suggested by a Health care Experienced to stop sexual action for health-related reasons or if you have at any time knowledgeable upper body soreness throughout sexual exercise.